AKT1 and neoplasm: PHLPP1 promotes apoptosis induced by mTOR2 by interfering with the downstream signal of phosphatidylinositol-3-kinase/protein-serine-threonine kinase (PI3K/Akt) signaling pathway and rat sarcoma protein/extracellular regulatory protein kinase pathway, thereby playing a role in inhibiting tumor growth [5].