CUL3 and Stroke: Moreover, the terms “protein ubiquitination” in the BP branch, “ubiquitin-protein transferase activity” in the MF branch, and “Cul3-RING ubiquitin ligase complex” in the CC branch are associated with protein ubiquitination, considered a key process in the ischemic cascade response after stroke, that has strong connections to pathophysiological processes such as apoptosis, autophagy, and inflammation.