In addition, circ_Dlgap3_1, circ_Tasp1_7, circ_Herc3_2, and circ_Chd2_24 targeted the antiapoptotic protein, Bcl-2, as well as apoptotic protease activating factor 1, supporting their participation in the apoptotic process after stroke. The gene discussed is HERC3; the disease is Stroke.