It is interesting to note that many of the ME-harboring epilepsy-associated genes are typically reported to be dysregulated in TLE patients’ brains, for example, SCN1A (Colosimo et al., 2007; Van Poppel et al., 2012; Kasperaviciute et al., 2013), BRD2 (Turnbull et al., 2005), and NF1 (Ren et al., 2016; Gales and Prayson, 2017). The gene discussed is SCN1A; the disease is epilepsy.