Th17 cells, characterized by the ability to produce IL-17A, have been extensively studied since their discovery over 10 years ago in many diseases, such as inflammatory bowel disease (IBD) (29), colorectal cancer (30), autoimmune arthritis (31), malignant pleural effusion (32), and hypoxia-induced pulmonary hypertension (33). The gene discussed is IL17A; the disease is inflammatory bowel disease.