Together, these data suggested that reconstitution of WT mice with the hematopoietic compartment of CXCL5-/- mice markedly decreased the levels of CXCL5 in infected lungs post infection, while reconstitution of CXCL5-/- mice with the hematopoietic compartment of WT mice resulted in CXCL5 production. The gene discussed is CXCL5; the disease is infection.