CALR and discoid lupus erythematosus: Furthermore, we observed that skin B cell enrichment scores remained significantly higher in DLE lesions compared to SCLE lesions among patients who tested negative for ANA (p=0.0010) or anti-dsDNA (p=0.0009) (Figure 4A), anti-Smith (p=0.0059) or anti-Ro (p=0.0131) (Figure 4B), or anti-phospholipid antibodies (p=0.0066) (Figure 4C).