The ILC2-related cytokine IL-13 could regulate leukocyte recruitment and induce differentiation of M2-like monocytes/macrophages, and could promote recovery of cardiac function after MI by secreting anti-inflammatory cytokines to stimulate new blood vessel formation and collagen deposition, thereby enhancing wound healing in the infarct area (26). The gene discussed is IL13; the disease is myocardial infarction.