Regarding the tricarboxylic acid cycle (Supplemental Figure S7B), six enzymes were differentially expressed in the cardiomyopathies; three of them with reduced expression in CCC and DCM samples as compared to control group: Fumarate hydratase (FUMH); Succinate dehydrogenase [ubiquinone] iron-sulfur subunit (DHSB) and Isocitrate dehydrogenase [NADP] (IDHP). This evidence concerns the gene FH and familial dilated cardiomyopathy.