Catalase (CATA) was upregulated only in CCC patients; immunoblotting analysis showed that the total catalase protein level was increased as compared to the other IC samples and the control group (Figure 5A); protein disulfide-isomerases PDIA1 and PDIA3 were upregulated in CCC and DCM. The gene discussed is P4HB; the disease is familial dilated cardiomyopathy.