DECR1 and familial dilated cardiomyopathy: The enzymes 2,4-dienoyl-CoA reductase (DECR) (Supplemental Figure S9) and 3,2-trans-enoyl-CoA isomerase (D3D2), which participate in the metabolism of unsaturated fatty enoyl-CoA esters, also showed reduced expression in samples of patients with CCC and DCM, and in samples of patients with CCC and IC, respectively, when compared to control samples.