Creatine kinase M (KCRM) and mitochondrial sarcomeric creatine kinase (KCRS), involved in the translocation of the ATP from the mitochondria to myofibrils, were found to be decreased in samples from patients with CCC and the other cardiomyopathies (Table 4 and Supplemental Figure S7D). This evidence concerns the gene CKMT2 and cardiomyopathy.