However, we observed no difference in total B cells, pro-B cells, pre-B cells, immature B cells and mature B cells in BM (Supplementary Figures 9A, B), as well as total B cells, immature B cells, marginal zone B cells and follicular B cells in spleens (Supplementary Figures 10A, B) between WT and IDO naïve mice or tumor-bearing mice. The gene discussed is IDO1; the disease is neoplasm.