The results indicated that TNFRSF10B, CD40, and TNFSF13B were risk factors for SCLC patients, while TNFRSF21, TNFRSF25, TNFRSF1B, RELT, and TNFSF14 were protective prognostic factors. Here, TNFRSF25 is linked to small cell lung carcinoma.