Phenotypically, the spleen and tumor-derived donors expressed similar levels of Bcl-2, TIM3, CXCR3, PD-1, and had undergone similar patterns for memory vs effector differentiation as determined by CD62L, CD127, and KLRG-1 (Figures 4E, F, and S4B, C). The gene discussed is BCL2; the disease is neoplasm.