INS and obesity due to melanocortin 4 receptor deficiency: As expected, MetS patients have higher blood pressure (BP), obesity-related indicators (WC and BMI), glucose metabolism-related parameters [FBG, 2-h blood glucose after glucose overload (2h-BG), HbA1c and AUCg], triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), FFA, FIns, 2-h serum insulin after glucose overload (2h-Ins), visceral adiposity index (VAI), and body adiposity index (BAI) and HOMA-IR than those of normal controls.