Similarly, patients with BC in stage IV, M1 classification, and T4 classification were discovered a low ITK expression and demonstrated the statistical significance (Stage IV vs. Stage I, Stage II and Stage III, p = 0.013, 0.031 and 0.023, respectively; T4 vs. T1, T2, and T3, p = 0.0012, 0.0044 and 0.0071, respectively; M0 vs. M1, p = 0.024). This evidence concerns the gene ITK and breast cancer.