ACE2 and Stroke: Second, SARS-CoV-2 can also infect endothelial (54) and myocardial cells (136) through ACE2 receptors expressed in the vascular endothelium, myocardium and arterial smooth muscles, causing endothelial cell apoptosis, inflammatory cell infiltration, myocardial inflammation and injury, which increases the risk of thrombosis and stroke.