TSPO and myeloid sarcoma: In a 4-year follow-up study, increased radioligand uptake in the perilesional NAWM predicted disability progression independent of relapse activity in MS, using mitochondrial 18-kDa translocator protein (TSPO)-PET, a marker of inflammation linked to microglial and macrophage activation in neurodegenerative and neuroinflammatory diseases such as MS (123).