VEGFA and preeclampsia: That is elevated in maternal serum in PE cases at 30 weeks and is sequestered during preeclampsia by excessive production of sFLT-1, resulting in endothelial dysfunction, suggesting an excess of VEGF production might play a role in preeclampsia by VEGF toxicity and stimulation of sFLT-1 production (Jena et al., 2020).