TNF and fibrosis: Over this second phase, pro-inflammatory cytokines [i.e., interleukin (IL)-2, IL-7, IL-10, granulocyte colony-stimulating factor (G-CSF), interferon gamma-induced protein 10 (IP-10), monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory proteins-1alpha (MIP-1A), and tumor necrosis factor-alpha (TNF)-α] increase significantly in the blood flow, which is called cytokine storms (Mehta et al., 2020), along with classic symptoms such as fever, cough, fibrosis, and on top of all these, lung inflammation as the major cause of lethal respiratory disorder (Zbinden-Foncea et al., 2020).