Therefore, this study detected the inflammation-related proteins in the liver tissue by TAA-induced, including IKKα/β, p-IKKα/β, IκBα, p-IκBα, NF-κB (p65), p-NF-κB (p-p65), TNF-α, IL-1β, which proved that DHM effectively inhibited the expression of these proteins, thereby reducing the inflammatory injury of liver fibrosis by TAA-induced. The gene discussed is CHUK; the disease is Hepatic fibrosis.