Curcumin was found to inhibit both NF-κB and Wnt signaling in cervical cancer while it also inhibited AP-1, NF-κB, and HPV E6 proteins in HPV-positive oral carcinoma, abolishing HPV transcription (Mishra et al., 2015; Ghasemi et al., 2019). Here, NFKB1 is linked to lip and oral cavity carcinoma.