Capecitabine is an oral prodrug of fluorouracil, which is converted into the active substance 5-fluorouracil (5-FU) by the higher level of thymidine phosphorylase (TP) in the tumor, it may provide better efficacy and safety due to non-cytotoxic of capecitabine and its intermediates (Ishitsuka et al., 1999). Here, TYMP is linked to neoplasm.