MAPT and neurodegenerative disease: Described hallmarks of both neurodegenerative diseases and neurotraumas are altered processing of APP, the formation of 40–42 aminoacids-long peptides (amyloid-β: Aβ-40, Aβ-42) and their aggregation in the β-amyloid plaques, as well as the excessive phosphorylation and truncation of the tau protein, its aggregation and loss of function as a stabilizer of microtubules (Walsh and Selkoe, 2004; Gong and Iqbal, 2008; Xu et al., 2021).