- comparison of the predicted phenotype from genotype and the measured MR of CYP2C19 found a statistically discordance (p < 0.0005), - of the 30 cancer patients with genotypic EM status, 11 were CYP2C19 PM, - no significant correlation between the levels of any individual cytokine (CRP, IL-1β, Il-1α, IL-6, TNF-α, TGF-β and CRP) and CYP2C19 metabolic activity. This evidence concerns the gene TGFB1 and cancer.