In addition, the IL1B gene SNPs (rs1143643 and rs1143627) chosen in our study have been demonstrated to be associated with other autoimmune inflammatory diseases, such as RA (Rong et al., 2020), ASSD (Ponce-Gallegos et al., 2020) and inflammatory bowel disease (IBD) (Liu et al., 2020). This evidence concerns the gene IL1B and rheumatoid arthritis.