For the rs1143627 polymorphism in the IL1B gene, the distribution frequencies of the 3 genotypes GG, GA and AA in the T1DM group were 20.8, 51.8 and 27.4%, respectively, while those in the healthy control group were 18.1, 52.7 and 29.2%, respectively. The gene discussed is IL1B; the disease is type 1 diabetes mellitus.