For the rs1143643 polymorphism of the IL1B gene, the distribution frequencies of the 3 genotypes CC, CT and TT in the T1DM group were 22.9, 49.5 and 27.6%, respectively, while those in the healthy control group were 21.3, 48.0 and 30.7%. Here, IL1B is linked to type 1 diabetes mellitus.