Although it was found that Lgals3bp may be a serological biomarker for acute dengue virus infection (Liu et al., 2016), acute hantavirus infection (Hepojoki et al., 2014), hepatitis C virus (HCV), human immunodeficiency virus (HIV) infection (Shaked et al., 2014; Yang et al., 2014; Rodríguez-Gallego et al., 2019), and hepatitis B virus-related hepatocellular carcinoma (Liu et al., 2017), the relationship between Lgals3bp and viral pneumonia is rarely investigated. This evidence concerns the gene LGALS3BP and hepatocellular carcinoma.