As shown in Figure 6, on the third day after viral infection and HYQ administration, the amounts of plasma protease C1 inhibitor (Serping1), glutathione peroxidase 3 (Gpx3), hemopexin (Hpx) and protein S100-A8 (S100a8) in the infected mouse blood increased compared to that of the control (p < 0.05), and HYQ inhibited the elevations of Serping1 and Gpx3 compared with that of the model group (p < 0.05). This evidence concerns the gene GPX3 and viral infectious disease.