While CSF1R rs10079250 polymorphism is not associated with the risk of PD in this cohort, CSF1 rs1058885 TT variant appears to be less frequent in PD patients than in control subjects (Chang et al., 2019), suggesting that CSF1/CSF1R neuroinflammatory signaling may also be involved in the pathogenesis of PD. This evidence concerns the gene CSF1R and Parkinson disease.