Currently, a compound partially selective to inhibit for CA-IX, referred to as SLC-0111, is in clinical trials, and it is likely it would operate as a therapy for multiple cancers, including glioblastoma (Boyd et al., 2017; Ilies and Winum, 2019; Shabana and Ilies, 2019; McDonald et al., 2020). Here, CA9 is linked to cancer.