DMPK and myotonic dystrophy type 1: In cultured primary hippocampal neurons and EpA960/CaMKII-Cre mice (a brain-specific DM1 model carrying 960 DMPK CTG repeats in the postnatal brain), expanded CUG repeats led to deubiquitination of cytoplasmic MBNL1, subsequent nuclear translocation, and morphological defects.