DMPK and myotonic dystrophy type 1: Meanwhile, the widespread distributions of mutant DMPK mRNA accumulated in nuclear foci in neurons, astrocytes, oligodendrocytes, as well as in human DM1 induced pluripotent stem cell (iPSC)-derived neural stem cells (NSCs) have been reported (Jiang et al., 2004; Hernández-Hernández et al., 2013a; Xia et al., 2013; Sicot et al., 2017).