With the similar analysis in the WGS cohort (sporadic late-onset PD cases), except for the established GBA (P = 5.80E-06), the rare putative damaging variant category of additional genes also shown a suggestive significant difference between cases and controls in our cohort, including GALNS (P = 0.01) and NAGA (P = 0.05) (Table 3). The gene discussed is GALNS; the disease is Parkinson disease.