The top 10 proteins with the most differences in level between AD and control (excluding keratin which is a contaminant) included the previously well-studied inflammatory marker, glial fibrillary protein (GFAP) (Laurent et al., 2018), and several markers of neurodegeneration; neurofilament light polypeptide (NfL), microtubule-associated protein-2 (MAP2), spectrin β-chain and β-chain, and β-synuclein (Yan et al., 2012; Bacioglu et al., 2016; Halbgebauer et al., 2020). Here, MAP2 is linked to Alzheimer disease.