This multiparametric MRI analysis of the CC demonstrated a specific involvement of its frontal subsections in PSP-RS, in accordance with the frontal involvement as step 4 in the proposed staging scheme for the neuropathological practice in PSP with increased neuronal tau pathology in the frontal lobe (Kovacs et al., 2020), while the CC itself has not been specifically addressed in the underlying neuropathological study. The gene discussed is MAPT; the disease is supranuclear palsy, progressive, 1.