Shen et al. (2020) used plasma biomarker to identify amyloid, tau, or neurodegeneration. Stockmann et al. (2020) designed a panel of structure-based Aβ plasma biomarkers as a prognostic tool for future progression from SCD to MCI or AD. Buegler et al. (2020) built digital biomarker-based prognostic models which predicted the risk to progress to dementia within 3 years. Those digital biomarker-based models are reviewed by Cavedoni et al. (2020). This evidence concerns the gene MAPT and Alzheimer disease.