Studies show that variants in ZNF292, which encodes a highly conserved zinc finger protein that is highly expressed in the developing human brain as a transcription factor, supporting its critical role in neural development, are associated with a spectrum of neurodevelopmental features including intellectual disability (ID), ASD, attention deficit and hyperactivity disorder (ADHD), among others (Mirzaa et al., 2020). The gene discussed is ZNF146; the disease is attention deficit-hyperactivity disorder.