Of the four predicted IDH-wildtype glioblastoma patients that lived longer than three years, two harbored hallmark + 7/ − 10 and EGFR amplification as well as co-gain of chromosomes 19 and 20, a documented marker for long-term survivors in IDH-wildtype glioblastoma [25] (Fig. 6G). Here, EGFR is linked to glioblastoma.