MKI67 and neoplasm: Previous studies have constructed CT/MRI based radiomics signature for biological behaviors prediction in BCa, including muscle-invasive status, lymph node metastasis, tumor stage, prognosis and therapeutic response [14–18], which suggests that radiomics features may potentially predict the expression of Ki67 in BCa for the sake of positive relationship between Ki67 expression and malignant progression [4–6, 9].