Then RIP assay was conducted to evaluate the ceRNA regulatory axis in HCC cells, and the results indicated that LOXL1-AS1, miR-3614-5p and YY1 were abundantly precipitated in anti-Ago2 groups, implying the co-existence of LOXL1-AS1/miR-3614-5p/YY1 in RISC complex (Fig. 3C). The gene discussed is YY1; the disease is hepatocellular carcinoma.