Our results showed that a large number of chemokines (i.e., IP-10/CXCL10, I-TAC/CXCL11, MIG/CXCL9, RANTES/CCL5, MIP-1α/CCL3, MIP-1β/CCL4, MIP-3α/CCL20, including the IL-8/CXCL8 and Eotaxin/CCL11-related chemokines) were found significantly increased in patients exhibiting high levels of anxiety and depressive symptoms. This evidence concerns the gene CXCL11 and Anxiety.