CD274 and neoplasm: To explore whether tumor glycolysis facilitates PD-L1 expression, we examined PD-L1 by immunostaining 26 pairs of biopsy samples obtained from the patients with PDAC, who had also been imaged using fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) as an indicator for metabolic activity of viable tumor cells.