Moreover, a recent study on systematic drug repurposing for COVID-19 based on machine learning has found that, among others, the VDR protein could have a protector effect over pathways affected by the SARS-CoV-2 infection16, suggesting a potential protecting role for VDES metabolites such as cholecalciferol, calcifediol or calcitriol. The gene discussed is VDR; the disease is COVID-19.