BRCA1 and breast cancer: There was no significant difference in allele frequency between BC cases and controls for FANCI c.1813C>T in a similar analysis of BCAC case-control data [45, 46] (BRCA1 c.4327C>T; p.R1443X and FANCI c.824T>C data was not available in the BCAC database) (Additional file 1: Table S5).