Three carriers of other candidate variants in FANCI (c.1573A>G; p.M525V, c.1264G>A; p.G422R, and c.1412C>G; p.P471R), with an average age of diagnosis of 52 years, also had a family history of OC (Table 2), where the carrier of p.M525V had no family history of BC. The gene discussed is FANCI; the disease is breast cancer.