Meanwhile, other similar researches further demonstrated that the active components of Huopo Xialing Decoction had anti-inflammatory, immune regulation, anti-pulmonary fibrosis effects, and might protect against COVID-19 by regulating the biological processes such as blocking the protein synthesis of SARS-CoV-2 virus, preventing the virus from entering the host cells, and regulating TNF, MAPK, TLR, NOD-like receptor, and HIF-1 signaling pathways [64, 65]. This evidence concerns the gene TNF and COVID-19.