KEAP1 and diabetic retinopathy: Our findings indicate the role of oxidative stress along with overweight, through increased TOS level, and also Keap1 polymorphism in diabetic retinopathy pathogenesis as the minor A allele of Keap1 was associated with lower Keap1 expression18 and also the presence of Keap1 AA genotype was correlated with lower GPx activity than CC genotype in our study.