38KLF5 is a transcription factor that is predominantly expressed in the intestinal crypt and regulates cell proliferation.39 It has also been implicated as an essential mediator of tumorigenesis by interacting with the RAS and Wnt signaling pathways.40,41 miR-204-5p has been reported to be a tumor suppressor42 and downregulates the expression of EZR in cell line studies.43EZR organizes the microvilli44 and pathologically is implicated in tumor invasion and metastasis.45,46. The gene discussed is EZR; the disease is neoplasm.