In contrast to previous reports on cellular models with induced DUX4 overexpression31 or mouse model,23 we did not find any enrichment in genes related to breast, lung, colon, thyroid cancer, gliomas and leukaemia, inflammation, apoptosis, or response to oxidative stress, most of which are not associated to FSHD clinical spectrum. This evidence concerns the gene DUX4 and thyroid cancer.