GPT and Fever: One participant receiving GLPG1972 300 mg experienced an increase in alanine aminotransferase levels on day 15 in study A (treatment was discontinued on day 16 and the TEAE resolved on day 24), and 2 participants receiving GLPG1972 1050 mg experienced several mild, nonserious TEAEs (including neck pain, pyrexia, and headache) from 10 days after dosing, which led to treatment withdrawal (all in study C).