GNMT and metabolic dysfunction-associated steatohepatitis: Human NASH dataset GSE17470 had top upregulated pathways including phospholipases, liver X receptor (LXR)/retinoid X receptor (RXR) activation, fatty acid β-oxidation I, and leukocyte extravasation, among which leukocyte extravasation was shared by the second human NASH and MCD+HFD, LXR/RXR activation was shared by HFCD, and fatty acid β-oxidation was shared by GNMT-KO and HFCD (Table 1, Supplementary Figure 1).