We also found that in GBM, LUSC, SARC, BRCA, STAD, and TGCT, MSH2 expression was significantly negatively correlated with stromal score; in CESC, LAML, GBM, KIRP, SARC, and UCEC, MSH2 expression and immune score were significantly negatively related. Here, MSH2 is linked to glioblastoma.