From Trial A: Birds challenged with yolk sac infection showed 80, 65, and 60% survival with IOI of CpG-ODN, poly I:C, and CPZ, respectively; and reduced early chick mortality. CpG-ODN also improved the clinical scores  From Trial B: The lower dosage (2.5 μg/egg) of CPZ is as potent as higher dosage (5 μg/egg). This evidence concerns the gene CPZ and infection.