The heat map indicated that the 11 TFs in 32 cancers were associated with altered PBK expression (Figure 4C): E2F1 in THYM (cor = 0.916), tripartite motif-containing 28 (TRIM28) in THYM (cor = 0.69), MYC in uveal melanoma (UVM) (cor = 0.577), and TATA-binding protein (TBP) in LIHC (cor = 0.497) were positively correlated with PBK level whereas signal transducer and activator of transcription 5A (STAT5A) and Spi-1 proto-oncogene (SPI1) showed negative correlations. The gene discussed is SPI1; the disease is cancer.