PBK and cancer: As shown in Figure 3, Kaplan–Meier plots identified that high expression of PBK indicated poorer prognosis in ACC (p < 0.001), KIRC (p = 0.01), KIRP (p = 0.001), LGG (p < 0.001), LIHC (p = 0.002), MESO (p < 0.001), and LUAD (p = 0.005), and Cox regression analyses confirmed that PBK is a high-risk gene in these cancer types, as well as in CHOL (HR = 1.941, p = 0.029), KICH (HR = 2.344, p < 0.001), DAAD (HR = 1.714, p < 0.001), and PCPG (HR = 3.843, p = 0.001) (Figure 3).