In our study detecting the expression of PBK in pan-cancer, we found that PBK is highly expressed in various types of cancers, including ACC, LGG, LUAD, and OV, as well as in tumor cell lines, while PBK is barely expressed in normal tissues, except for bone marrow and the testis, which is consistent with previous reports that PBK is abnormally expressed in tumor tissues and proliferating cells but is hardly detected in normal tissues. This evidence concerns the gene PBK and neoplasm.