The results revealed that the scores associated with the T-cell inflammation signature (TIS) and tumor immune dysfunction and exclusion (TIDE) profiles of immune checkpoints in the low-risk group were higher than those in the high-risk group, such as APC co-inhibition, cytokine–cytokine receptor (CCR), CD8+ T cells, Check-point, Cytolytic activity, HLA, Inflammation-promoting, MHC class I, Parainflammation, T cell co-inhibition, T cell co-stimulation, T helper cells, Tfh, Th1 cells, Th2 cells, TIL, Treg, Type I IFN response, and Type II IFN response (Figure 10A). Here, CD8A is linked to neoplasm.